Transparency
Market Research Reports included a detailed market survey and analysis trends
on “Ubiquitin Proteasome Market”.
This report also includes more info about basic overview of the industry
including definitions, applications and global market industry structure.
Proteasomes are the protein complexes present inside eukaryotes and a few
prokaryotes. Proteolysis is the main function of these proteasomes, in which,
unnecessary or damaged proteins are degraded by the breakage of peptide bonds
catalyzed by enzymes called as proteases. This overall system of protein
degradation is known as ubiquitin proteasome system.
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Ubiquitin
proteasome system plays an important role in a variety of basic cellular
processes and signaling pathways such as regulation of cell cycle, cell
division and differentiation, DNA repair, transcriptional regulation,
regulation of the immune responses and modulation of cell surface receptors.
The regular degradation of proteins is crucial for maintenance of almost all
biological processes including cell proliferation, cell metabolism and
apoptosis.
Research
in the field of ubiquitin proteasome is expanding exponentially. For instance,
intensive research is going on in the field of applications of ubiquitin
proteasome system in the treatment of cancer, as the pharmacological inhibition
properties of proteasomes can be effective in cancer treatment. Potential sites
of therapeutic interventions are also under research and the selective
inhibition of disease specific components is also being studied for the purpose
of developing treatments for diseases such as neurodegenerative disorders. This
indicates a bright future market potential depending upon the time required for
commercialization. Currently, there is only one approved ubiquitin proteasome
system product available in the market named Velcade. In 2009, total sales of
Velcade were estimated to be 1.4 billion and being the only approved drug, its
sales are expected to achieve growth at a high compounded annual growth rate.
Although
a lot of basic knowledge about the mechanism of ubiquitin proteasome systems is
available, its real commercial potential has not yet been fully discovered. The
market for ubiquitin proteasome can be divided into four segments on the basis
of geography, namely North America, Europe, Asia-Pacific and Rest of the World.
Some of the companies
involved in the research and development of ubiquitin proteasome systems are
Johnson & Johnson, F. Hoffmann-La Roche Ltd., Novelix Pharmaceuticals,
Inc., GlaxoSmithKline Pharmaceuticals Ltd. and Onyx Pharmaceuticals, Inc.
This research report
analyzes this market depending on its market segments, major geographies, and
current market trends. Geographies analyzed under this research report
include
- North America
- Asia Pacific
- Europe
- Rest of the World
This report provides
comprehensive analysis of
- Market growth drivers
- Factors limiting market growth
- Current market trends
- Market structure
This
report is a complete study of current trends in the market, industry growth
drivers, and restraints. It provides market projections for the coming years.
It includes analysis of recent developments in technology, Porter’s five force
model analysis and detailed profiles of top industry players. The report also
includes a review of micro and macro factors essential for the existing market
players and new entrants along with detailed value chain analysis.
Reasons for Buying this
Report
- This report provides pin-point
analysis for changing competitive dynamics
- It provides a forward looking
perspective on different factors driving or restraining market
growth
- It provides a technological growth
map over time to understand the industry growth rate
- It provides a seven-year forecast assessed on the basis of how the market is predicted to grow
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