The
global antibacterial drugs market was valued at USD 43.55billion in
2012 and is expected to grow at a CAGR of0.3% from 2013 to 2019, to
reach an estimated value of USD 45.09billion in 2019.
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An
antibacterial drug has been utilized by humans since the discovery of
the first antibiotic penicillin in 1928 and has grown into a
multi-billion dollar market since. These drugs treat infectious
diseases caused by gram positive, gram negative, aerobic and
anaerobic bacteria, which cannot be treated by any other method
unlike other diseases, where substitute methodologies are
available.This property has made antibacterial drugs an indispensable
part of human healthcare.
Antibacterial
drugs are classified into seven major classes, namely,
aminoglycosides, β-Lactams, tetracyclines, sulfonamides, quinolones,
macrolides and phenicols. The β-lactams class was the largest
segment of the global antibacterial drugs market in 2012,with 57%
share.Quinolones was identified as the second largest class, which
held a share of 16.6% of the global antibacterial drugs market in
2012 and is expected to report a negative CAGR during the forecast
period. This decline in revenue will be primarily witnessed due to
sales erosion from patent expiries, evolution of resistant strains of
bacteria and rising concerns regarding tendon ruptures and tendon
damage from fluoroquinolones therapy.However, the demand for
macrolides and quinolones/fluoroquinolones classes will remain high
during the forecast period, due to their usage in treating a large
number of infections coupled with expected launch of pipeline drugs
in these classes during the forecast period.
Factors
such as increasing prevalence of infectious diseases and rising
demand for effective as well as affordable antibacterial drugs
especially from emerging economies of Asia-Pacific, Latin America,
Middle East and Africa are the major growth drivers for the
antibacterial drugs market. Globally, rise in elderly population is
also being considered as one of the major growth factors as it will
indirectly increase the demand for various antibacterial drugs. The
demand for antibacterial drugs will continue to rise regardless of
presence of a wide range of antibacterial drugs. This is mainly due
to increased prevalenceof resistant species which demand development
of innovative molecules.
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In
2012, Asia-Pacific held the largest share of the revenue generated by
the global antibacterial drugs market. This region is also set to
experience the highest growth rate during the forecast period 2013 to
2019. This is becausethe region accounts for the largest infected
population in the world, by a variety of bacterial infections like
pneumonia, tuberculosis, tetanus and others. Other factors
includeincreasing multi-drug resistant bacterial strains, increasing
availability of generic drugs and increasing purchasing power of the
people of this region. India, one of the key markets in the
Asia-Pacific region, isfamous for being the largest generic drug
manufacturing nation. North America held the second largest revenue
share, followed by Europe in the antibacterial drugs market in 2012.
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At
present, certain novel compounds are under investigation in both
preclinical and clinical settings for the treatment of newly evolving
drug-resistant bacterial species.Some of the major candidates such as
Dalvance (Durata Therapeutics), tedizolidand surotomycin(Cubist
Pharmaceuticals), and others are currently in phase III clinical
trials. These drugs promise to provide improved efficacy, shorter
onset of action and fewer side effects as compared to the currently
available antibacterial drugs. Hence, expected launch of these drugs
during the forecast period is anticipated to have a profound impact
on the growth of the overall antibacterial drugs market.
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AstraZeneca
plc, Bayer AG, Bristol-Myers Squibb Company, Eli Lilly and Company,
Forest Laboratories, Inc., GlaxoSmithKline plc, Johnson &
Johnson, Merck & Co., Inc., Novartis AG, Pfizer, Inc., and Sanofi
are the major players operating in the global antibacterial drugs
market. With very few patented products currently available in this
market, the market is currently dominated by generic manufacturers to
a great extent. With respect to the key revenue generating drugs
(branded and generic) of this market, Pfizer, Inc. accounted for the
largest market share in 2012, followed by Merck & Co., Inc. and
GlaxoSmithKline plc.
The
global antibacterial drugs market is segmented as follows:
Antibacterial
Drugs Market, by Class
Aminoglycosides
β-Lactams
Tetracyclines
Sulfonamides
Quinolones/Fluoroquinolones
Macrolides
Phenicols
Antibacterial
Drugs Market, by Geography
North
America
Europe
Asia-Pacific
Rest
of the World (RoW)
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